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Agoxin

Tab. Agoxin 250 mcg

SKU PRO-03-0001012
Dosage Tab.
Brand Name Agoxin
Generic Digoxin
Strength 250 mcg
Manufacturer Aristopharma
Pack Piece MRP ARTO Price
Single 1 1.09 BDT 1.09 BDT
Box 100 pcs 108.88 BDT 108.88 BDT
Cartoon X X X

Information: Tab. Agoxin 250 mcg

Therapeutic action – Cardiotonic Indications – Supraventricular arrhythmias (fibrillation, flutter, paroxysmal tachycardia) – Heart failure Presentation – 62.5 µg (0.0625 mg) and 250 µg (0.25 mg) tablets Also comes in 50 µg/ml oral solution (0.05 mg/ml). Dosage – Adult: • loading dose: 750 to 1500 µg (0.75 to 1.5 mg) in 3 to 4 divided doses. Do not exceed 1500 µg during the first 24 hours. • maintenance dose: 125 to 250 µg/day (0.125 to 0.25 mg) once daily or in 2 divided doses – Reduce the dose by one half in elderly patients and in patients with renal impairment. Duration – According to clinical response Contra-indications, adverse effects, precautions – Do not administer to patients with bradycardia, ill defined arrhythmia, coronary artery disease. – It is essential to monitor pulse in the initial stage of treatment. – Narrow margin between therapeutic and toxic dose. – May cause in the event of overdose: gastrointestinal disturbances (nausea, vomiting, diarrhoea), blurred vision, headache, confusion, conduction and rhythm disorders. If so, reduce dose or stop treatment. – Do not combine with calcium, particularly by IV route (serious arrhythmias). – Monitor combination with: • amiodarone, macrolides, itraconazole, quinine, chloroquine (increased digoxin concentration); • potassium-depleting drugs: diuretics, corticoids, amphotericin B (increased risk of digoxin toxicity). – Monitor if possible serum potassium level in patients taking potassium-depleting drugs and serum creatinine level in patients with renal impairment. – Do not administer simultaneously with antacids such as aluminium hydroxide, etc., administer 2 hours apart. – Pregnancy: no contra-indication – Breast-feeding: no contra-indication Remarks – A loading dose may be administered in arrhythmias if a rapid digitalisation is required. It is usually not necessary for heart failure. – Storage: below 25°C – https://en.wikipedia.org/wiki/Digoxin

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