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Tab. Opsonil 50 mg

SKU PRO-49-0011791
Dosage Tab.
Brand Name Opsonil
Generic Chlorpromazine Hydrochloride
Strength 50 mg
Manufacturer Opsonin Pharma Limited
Pack Piece MRP ARTO Price
Single 1 0.60 BDT 0.6 BDT
Box 100 pcs 60.00 BDT 60 BDT
Cartoon X X X

Information: Tab. Opsonil 50 mg

Therapeutic action – Sedative antipsychotic (neuroleptic) Indications – Acute or chronic psychosis – Severe anxiety not controlled by benzodiazepines Presentation – 25 mg tablet Also comes in 100 mg tablets. Dosage – Acute or chronic psychosis Adult: initial dose of 75 mg/day in 3 divided doses; if necessary, the dose may be gradually increased up to 300 mg/day in 3 divided doses (max. 600 mg/day). Once the patient is stable, the maintenance dose is administered once daily in the evening. – Severe anxiety not controlled by benzodiazepines Adult: 75 to 150 mg/day in 3 divided doses – Whatever the indication, reduce the dose by half in elderly patients. – Use the lowest effective dose, especially in the event of prolonged treatment. Duration – Acute psychosis: minimum 3 months; chronic psychosis: minimum one year. The treatment should be discontinued gradually (over 4 weeks). If signs of relapse occur, increase the dose. – Severe anxiety: maximum 4 weeks. Contra-indications, adverse effects, precautions – Do not administer to patients with closed-angle glaucoma, prostate disorders; to elderly patients with dementia (e.g. Alzheimer's disease). – Administer with caution and carefully monitor use in patients > 60 years; patients with epilepsy, chronic constipation, renal or hepatic impairment, Parkinson's disease, myasthenia gravis. – May cause: • drowsiness (caution when driving/operating machinery), orthostatic hypotension, sexual dysfunction; • anticholinergic effects (dry mouth, blurred vision, urinary retention, constipation, tachycardia); • extrapyramidal syndrome, early or tardive dyskinesia, photosensitivity (patients must protect themselves from sunlight), jaundice; neuroleptic malignant syndrome (unexplained hyperthermia with neuromuscular disorders), rare but requiring immediate treatment discontinuation. – In the event of extrapyramidal symptoms, combine with biperiden. – Avoid or monitor combination with: drugs which lower the seizure threshold (mefloquine, chloroquine, tramadol, tricyclic or SSRI antidepressants); CNS depressants (opioid analgesics, sedatives, H1 antihistamines, etc.); drugs known to have anticholinergic effects (amitriptyline, atropine, clomipramine, promethazine, etc.); antidiabetics, lithium. – Avoid alcohol during treatment. – Chlorpromazine is irritating to the skin/mucous membranes: do not crush tablets. – Pregnancy: re-evaluate whether the treatment is still necessary; if it is continued, monitor the newborn infant for extrapyramidal and/or anticholinergic effects (tremor, abdominal distension, hyperexcitability, etc.) if the mother was under high dose treatment in the 3rd trimester. – Breast-feeding: avoid Remarks – In the event of agitation or aggressiveness in patients under other antipsychotic treatment (e.g. risperidone or haloperidol), chlorpromazine may be administered at the dose of 75 to 150 mg/day in 3 divided doses for a few days. – Chlorpromazine produces less extrapyramidal symptoms than haloperidol but orthostatic hypotension and anticholinergic effects are more frequent. – Storage: below 25°C https://en.wikipedia.org/wiki/Chlorpromazine

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